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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-OSMR Reference Antibody (vixarelimab)
Anti-OSMR Reference Antibody (vixarelimab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | Q99650 |
| Reactivity | Cynomolgus, Human |
| Clonality | Monoclonal |
| Isotype | IgG4SP |
| Calculated MW | 145 KDa |
| Target/Specificity | OSMR |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | OSMR |
|---|---|
| Synonyms | OSMRB |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in keratinocytes (at protein level) (PubMed:21261663). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells (PubMed:8999038) |
Research Areas
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$ 385.00
Cat# APR10201
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