Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
COVID19
>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Recombinant Antibodies   >   Anti-CLDN6 Reference Antibody (IMAB027)   

Anti-CLDN6 Reference Antibody (IMAB027)

Recombinant Antibody

     
  •  - Anti-CLDN6 Reference Antibody (IMAB027) APR10143
    Anti-CLDN6 Reference Antibody (IMAB027) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-CLDN6 Reference Antibody (IMAB027) APR10143
    The purity of Anti-CLDN6 Reference Antibody (IMAB027)is more than 98.41% ,determined by SEC-HPLC.
    detail
  •  - Anti-CLDN6 Reference Antibody (IMAB027) APR10143
    Immobilized human CLDN6 VLP at 8 µg/mL can bind Anti-CLDN6 Reference Antibody (IMAB027),EC50=0.001599 µg/mL
    detail
  •  - Anti-CLDN6 Reference Antibody (IMAB027) APR10143
    Human CLDN6 CHO cells were stained with Anti-CLDN6 Reference Antibody (IMAB027) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC199=4.342 nM
    detail
  •  - Anti-CLDN6 Reference Antibody (IMAB027) APR10143
    Anti-CLDN6 Reference Antibody (IMAB027)-induced ADCC activity was evaluated using Human CD16a (158V) (Luc) Jurkat Reporter Cell. The max induction fold was approximately 14.16
    detail
  •  - Anti-CLDN6 Reference Antibody (IMAB027) APR10143
    Anti-CLDN6 Reference Antibody (IMAB027) by huCLDN6-HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 60% at antibody concentration of 1 nM.
    detail
  •  - Anti-CLDN6 Reference Antibody (IMAB027) APR10143
    IMAB027 inhibited the tumor growth of OV90 on Balb/c nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 50.7% at 5 mpk at D34.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession P56747
Reactivity Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 144.42 KDa
Additional Information
Target/Specificity CLDN6
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name CLDN6
Function Plays a major role in tight junction-specific obliteration of the intercellular space.
Cellular Location Cell junction, tight junction {ECO:0000250|UniProtKB:Q9Z262}. Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines
Research Areas
Citations (0)
citation

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
FeedBack
Abcepta welcomes feedback from its customers.

If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abcepta.com.

$ 365.00
Cat# APR10143
Size:
Quantity:
Availability: 4 weeks
Bulk Size

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abcepta, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions
"