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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-TNFSF7 / CD27L / CD70 Reference Antibody (Vorsetuzumab mafodotin)
Anti-TNFSF7 / CD27L / CD70 Reference Antibody (Vorsetuzumab mafodotin)
Recombinant Antibody
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- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | P32970 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 146.1 KDa |
| Target/Specificity | TNFSF7 / CD27L / CD70 |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | MMAF |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | CD70 (HGNC:11937) |
|---|---|
| Function | Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells (PubMed:28011863, PubMed:28011864, PubMed:8387892). The CD70- CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells (PubMed:28011863, PubMed:28011864). |
| Cellular Location | Cell membrane; Single-pass type II membrane protein |
Research Areas
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$ 385.00
Cat# APR10096
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