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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-CSF2Rb / CD131 Reference Antibody (CSL311)
Anti-CSF2Rb / CD131 Reference Antibody (CSL311)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | P32927 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | IgG4 |
| Calculated MW | 144.66 KDa |
| Target/Specificity | CSF2Rb / CD131 |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | CSF2RB |
|---|---|
| Synonyms | IL3RB, IL5RB |
| Function | Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA (PubMed:1495999). In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK- STAT pathway (PubMed:9516124). |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
Research Areas
Citations (0)
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Application Protocols
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$ 365.00
Cat# APR10062
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