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Anti-CDH6 / K-Cadherin Reference Antibody (HKT288)

Recombinant Antibody

     
  •  - Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) APR10022
    Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) APR10022
    The purity of Anti-CDH6 / K-Cadherin Reference Antibody (HKT288)is more than 97.93% ,determined by SEC-HPLC.
    detail
  •  - Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) APR10022
    Immobilized Cyno CDH6 His at 2  µg/mL can bind Anti-CDH6 / K-Cadherin Reference Antibody (HKT288),EC50=0.006944 µg/mL.
    detail
  •  - Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) APR10022
    Human CDH6 HEK293(A6) cells were stained with Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC71=0.08624 ug/mL
    detail
  •  - Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) APR10022
    The endocytosis ratio HKT288 by Hu-CDH6-HEK293(A6) increased with the increase of antibody concentration, and the Internalization Rate (%) reached 93% at antibody concentration of 2 nM.
    detail
  •  - Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) APR10022
    HKT288 induced OVCAR3 Luciferase activity was evaluated using huCD16a(V158)-NF-AT-Jurkat Reporter Cell. The EC50 was approximately 0.6792 nM.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession P55285
Reactivity Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 144.24 KDa
Additional Information
Target/Specificity CDH6 / K-Cadherin
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name CDH6
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas
Research Areas
Citations (0)
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$ 365.00
Cat# APR10022
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