Anti-ADAM9 Reference Antibody (Imgc936)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, E, FTA |
---|---|
Primary Accession | Q13443 |
Reactivity | Cynomolgus, Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 147.62 KDa |
Target/Specificity | ADAM9 |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | ADAM9 |
---|---|
Synonyms | KIAA0021, MCMP, MDC9, MLTNG |
Function | Metalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell- matrix interactions and regulate the motility of cells via interactions with integrins. |
Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein |
Tissue Location | Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart |
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