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Anti-CCN2 / CTGF Reference Antibody (pamrevlumab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | P29279 |
| Reactivity | Rat, Human, Mouse, Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 144.86 KDa |
| Target/Specificity | CCN2 / CTGF |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | CCN2 (HGNC:2500) |
|---|---|
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor- induced DNA synthesis. |
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P29268}. Secreted {ECO:0000250|UniProtKB:P29268} |
| Tissue Location | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
Research Areas
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$ 385.00
Cat# APR10017
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