TdT
Rabbit Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC |
---|---|
Primary Accession | P04053 |
Host | Rabbit |
Clonality | Monoclonal |
Calculated MW | 58536 Da |
Gene ID | 1791 |
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Gene Name | DNTT |
Other Names | DNA nucleotidylexotransferase, 2.7.7.31, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase, DNTT, TDT {ECO:0000303|PubMed:11473582} |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TdT is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DNTT |
---|---|
Synonyms | TDT {ECO:0000303|PubMed:11473582} |
Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
Cellular Location | Nucleus. |

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