CD16
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC |
---|---|
Primary Accession | P08637 |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 29089 Da |
Gene ID | 2214 |
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Gene Name | FCGR3A |
Other Names | Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A {ECO:0000303|PubMed:23006327} |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CD16 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FCGR3A {ECO:0000303|PubMed:23006327} |
---|---|
Synonyms | CD16A, FCG3, FCGR3, IGFR3 |
Function | Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Secreted. Note=Exists also as a soluble receptor |
Tissue Location | Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts |
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