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CNPY2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q9Y2B0 |
| Other Accession | Q9QXT0 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20652 Da |
| Antigen Region | 134-162 aa |
| Gene ID | 10330 |
|---|---|
| Other Names | Protein canopy homolog 2, MIR-interacting saposin-like protein, Putative secreted protein Zsig9, Transmembrane protein 4, CNPY2, MSAP, TMEM4, ZSIG9 |
| Target/Specificity | This CNPY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-162 amino acids from the C-terminal region of human CNPY2. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CNPY2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CNPY2 |
|---|---|
| Synonyms | MSAP, TMEM4, ZSIG9 |
| Function | Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation. |
| Cellular Location | Endoplasmic reticulum {ECO:0000255|PROSITE- ProRule:PRU10138} |
| Tissue Location | Expressed in different tissues. Highest levels are detected in adult placenta, liver and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CNPY2 is positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.
References
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Bornhauser, B.C., et al. Cell. Mol. Life Sci. 62(11):1260-1266(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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