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5NT1A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9BXI3 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41021 Da |
| Antigen Region | 91-119 aa |
| Gene ID | 84618 |
|---|---|
| Other Names | Cytosolic 5'-nucleotidase 1A, cN1A, Cytosolic 5'-nucleotidase IA, cN-I, cN-IA, NT5C1A |
| Target/Specificity | This 5NT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human 5NT1A. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | 5NT1A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NT5C1A |
|---|---|
| Function | Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside (PubMed:11133996, PubMed:34814800, PubMed:7599155, PubMed:8967393). AMP is the major substrate but can also hydrolyze dCMP and IMP (PubMed:11133996, PubMed:34814800, PubMed:7599155, PubMed:8967393). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates.
References
Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009)
Lechward, K., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(4):280-284(2009)
Fyrberg, A., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1201-1204 (2006) :
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