LXN Antibody
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q9BS40 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 25750 Da |
Gene ID | 56925 |
---|---|
Other Names | Latexin, Endogenous carboxypeptidase inhibitor, ECI, Protein MUM, Tissue carboxypeptidase inhibitor, TCI, LXN |
Target/Specificity | This LXN antibody is generated from rabbits immunized with human LXN recombinant protein. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LXN Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LXN |
---|---|
Function | Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation. |
Cellular Location | Cytoplasm. |
Tissue Location | Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
LXN encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.
References
Pallares, I., et al. Proc. Natl. Acad. Sci. U.S.A. 102(11):3978-3983(2005)
Liu, Q., et al. Mol. Biol. Rep. 27(4):241-246(2000)
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