PGP Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
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Primary Accession | A6NDG6 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 34006 Da |
Antigen Region | 33-62 aa |
Gene ID | 283871 |
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Other Names | Phosphoglycolate phosphatase, PGP, PGPase, PGP |
Target/Specificity | This PGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human PGP. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PGP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PGP (HGNC:8909) |
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Function | Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity). |
Tissue Location | Detected in all tissues including red cells, lymphocytes and cultured fibroblasts (at protein level). The highest activities occur in skeletal muscle and cardiac muscle |
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Provided below are standard protocols that you may find useful for product applications.
References
Garcia, M.G., et al. Leuk. Res. 33(2):288-296(2009)
Lin, Y.C., et al. Ther Drug Monit 28(5):668-672(2006)
de Leon, J., et al. J Clin Psychopharmacol 25(5):448-456(2005)
Turzanski, J., et al. Exp. Hematol. 33(1):62-72(2005)
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