LYPD1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q8N2G4 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 15240 Da |
Antigen Region | 93-122 aa |
Gene ID | 116372 |
---|---|
Other Names | Ly6/PLAUR domain-containing protein 1, Putative HeLa tumor suppressor, PHTS, LYPD1, LYPDC1 |
Target/Specificity | This LYPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the C-terminal region of human LYPD1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LYPD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LYPD1 |
---|---|
Synonyms | Lynx2 {ECO:0000303|PubMed:33019770}, LYP |
Function | Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2- containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety. |
Cellular Location | Cell membrane; Lipid-anchor, GPI- anchor |
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Provided below are standard protocols that you may find useful for product applications.
References
Yu, D.H., et al. Exp. Cell Res. 312(6):865-876(2006)
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
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