YIPF5 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | Q969M3 |
Other Accession | Q4R5M4 |
Reactivity | Human, Mouse |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27989 Da |
Antigen Region | 21-49 aa |
Gene ID | 81555 |
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Other Names | Protein YIPF5, Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5, Smooth muscle cell-associated protein 5, SMAP-5, YIP1 family member 5, YPT-interacting protein 1 A, YIPF5, FINGER5, YIP1A |
Target/Specificity | This YIPF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human YIPF5. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | YIPF5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | YIPF5 (HGNC:24877) |
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Synonyms | FINGER5, YIP1A |
Function | Plays a role in transport between endoplasmic reticulum and Golgi. In pancreatic beta cells, required to transport proinsulin from endoplasmic reticulum into the Golgi (PubMed:33164986). |
Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9EQQ2}; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle {ECO:0000250|UniProtKB:Q5XID0}. Note=Enriched at the endoplasmic reticulum exit sites (By similarity). Incorporated into COPII-coated vesicles (By similarity). {ECO:0000250|UniProtKB:Q5XID0, ECO:0000250|UniProtKB:Q9EQQ2} |
Tissue Location | Ubiquitously expressed with abundant expression in pancreatic tissue, islets, beta cells, and brain. Highly expressed in coronary smooth muscles. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in transport between endoplasmic reticulum and Golgi.
References
?Koskinen, L.L., et al. Tissue Antigens 74(5):408-416(2009)
?Kano, F., et al. J. Cell. Sci. 122 (PT 13), 2218-2227 (2009) :
?Yoshida, Y., et al. Exp. Cell Res. 314(19):3427-3443(2008)
?Jin, C., et al. Biochem. Biophys. Res. Commun. 334(1):16-22(2005)
?Stolle, K., et al. Gene 351, 119-130 (2005) :
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