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TBR1 Recombinant Rabbit mAb
TBR1 Recombinant Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q64336 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Recombinant |
| Calculated MW | 73940 Da |
| Gene ID | 21375 |
|---|---|
| Other Names | T-box brain protein 1, T-brain-1, TBR-1, TES-56, Tbr1 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | Tbr1 |
|---|---|
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection (PubMed:11239428, PubMed:21285371, PubMed:9883721). As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons (PubMed:21285371). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q16650}. |
| Tissue Location | Expressed in the developing and adult cortex (PubMed:11239428). Expressed in the olfactory bulbs (PubMed:9883721) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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