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MUC6 Mouse mAb
MUC6 Mouse mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q6W4X9 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Calculated MW | 257051 Da |
| Gene ID | 4588 |
|---|---|
| Other Names | Mucin-6, MUC-6, Gastric mucin-6, MUC6 |
| Dilution | IHC-P=1:100-500,IF=1:100-500,IHC-F=1:100-500 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | MUC6 |
|---|---|
| Function | May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct. |
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Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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