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NPY2R Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P49146 |
| Other Accession | P97295 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42731 Da |
| Antigen Region | 19-45 aa |
| Gene ID | 4887 |
|---|---|
| Other Names | Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor, NPY2R |
| Target/Specificity | This NPY2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human NPY2R. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NPY2R Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NPY2R |
|---|---|
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
References
?Shoblock, J.R., et al. Psychopharmacology (Berl.) 208(2):265-277(2010)
?Arnett, D.K., et al. J. Hypertens. 27(8):1585-1593(2009)
?Zhang, J., et al. Zhonghua Liu Xing Bing Xue Za Zhi 30(7):695-698(2009)
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