DIRAS1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | O95057 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 22329 Da |
Antigen Region | 109-136 aa |
Gene ID | 148252 |
---|---|
Other Names | GTP-binding protein Di-Ras1, Distinct subgroup of the Ras family member 1, Ras-related inhibitor of cell growth, Rig, Small GTP-binding tumor suppressor 1, DIRAS1, GBTS1, RIG |
Target/Specificity | This DIRAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-136 amino acids from the Central region of human DIRAS1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DIRAS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DIRAS1 |
---|---|
Synonyms | GBTS1, RIG |
Function | Displays low GTPase activity and exists predominantly in the GTP-bound form. |
Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
Tissue Location | Highly expressed in heart and brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Kontani, K., et al. J. Biol. Chem. 277(43):41070-41078(2002)
Ellis, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 99(15):9876-9881(2002)
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