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HAVCR1 Rabbit pAb
HAVCR1 Rabbit pAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q5QNS5 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33361 Da |
| Gene ID | 171283 |
|---|---|
| Other Names | Hepatitis A virus cellular receptor 1 homolog, HAVcr-1, Kidney injury molecule 1, KIM-1, T cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T cell membrane protein 1, T-cell immunoglobulin mucin receptor 1, TIM-1, CD365, Havcr1, Kim1, Tim1, Timd1 |
| Dilution | WB=1:500-2000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | Havcr1 |
|---|---|
| Synonyms | Kim1, Tim1, Timd1 |
| Function | Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions (PubMed:21821911, PubMed:25645598, PubMed:32668241). As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses (PubMed:24703780). Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease (PubMed:24703780). Regulates also expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10 (PubMed:25582854, PubMed:25645598). Acts as a regulator of T-cell proliferation (PubMed:15793576). May play a role in kidney injury and repair (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q96D42}; Single-pass type I membrane protein |
| Tissue Location | Expressed by stimulated T-cells. Expressed during primary antigen stimulation (PubMed:11725301). Expressed at higher levels on B rather than T-cells, both constitutively and after activation (PubMed:21821911). |
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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$ 385.00
Cat# AP93922
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