HSCB (11S6) Mouse Monoclonal antibody
HSCB (11S6) Mouse Monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC |
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Primary Accession | Q8IWL3 |
Reactivity | Rat, Human, Mouse, Monkey, Dog |
Clonality | Monoclonal |
Calculated MW | 27422 Da |
Gene ID | 150274 |
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Other Names | Iron-sulfur cluster co-chaperone protein HscB, DnaJ homolog subfamily C member 20, Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic, C-HSC20, Iron-sulfur cluster co-chaperone protein HscB, mitochondrial, HSCB (HGNC:28913), DNAJC20, HSC20 |
Storage Conditions | -20℃ |
Name | HSCB (HGNC:28913) |
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Synonyms | DNAJC20, HSC20 |
Function | [Iron-sulfur cluster co-chaperone protein HscB, mitochondrial]: Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria (PubMed:20668094). Required for incorporation of iron- sulfur clusters into SDHB, the iron-sulfur protein subunit of succinate dehydrogenase that is involved in complex II of the mitochondrial electron transport chain (PubMed:26749241). Recruited to SDHB by interaction with SDHAF1 which first binds SDHB and then recruits the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20 (PubMed:26749241). Plays an essential role in hematopoiesis (By similarity). |
Cellular Location | [Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic]: Cytoplasm |
Tissue Location | Expressed in lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart. |

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