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SNX10 (18M9) Mouse Monoclonal antibody
SNX10 (18M9) Mouse Monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9Y5X0 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Calculated MW | 23598 Da |
| Gene ID | 29887 |
|---|---|
| Other Names | Sorting nexin-10, SNX10 |
| Storage Conditions | -20℃ |
| Name | SNX10 |
|---|---|
| Function | Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption. |
| Cellular Location | Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=May also localize to nucleus and endoplasmic reticulum |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene may play a role in regulating endosome homeostasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
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