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PPA2 (6W7) Mouse Monoclonal antibody

PPA2 (6W7) Mouse Monoclonal antibody

     
  •  - PPA2 (6W7) Mouse Monoclonal antibody AP93864
    Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PPA2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, AP93864) (1:150)
    detail
  •  - PPA2 (6W7) Mouse Monoclonal antibody AP93864
    Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-PPA2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, AP93864) (1:150)
    detail
  •  - PPA2 (6W7) Mouse Monoclonal antibody AP93864
    Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PPA2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, AP93864) (1:150)
    detail
  •  - PPA2 (6W7) Mouse Monoclonal antibody AP93864
    Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-PPA2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, AP93864) (1:150)
    detail
  •  - PPA2 (6W7) Mouse Monoclonal antibody AP93864
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPA2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PPA2 (Cat# AP93864)(1:2000). Positive lysates (100ug) and (20ug) can be purchased separately from biodragon.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q9H2U2
Reactivity Human
Clonality Monoclonal
Calculated MW 37920 Da
Additional Information
Gene ID 27068
Other Names Inorganic pyrophosphatase 2, mitochondrial, 3.6.1.1, Pyrophosphatase SID6-306, Pyrophosphate phospho-hydrolase 2, PPase 2, PPA2
Storage Conditions-20℃
Protein Information
Name PPA2
Function Hydrolyzes inorganic pyrophosphate (PubMed:27523597). This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function (PubMed:27523598).
Cellular Location Mitochondrion.
Tissue Location Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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$ 385.00
Cat# AP93864
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