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PRCC (7H14) Mouse Monoclonal antibody
PRCC (7H14) Mouse Monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q92733 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Calculated MW | 52418 Da |
| Gene ID | 5546 |
|---|---|
| Other Names | Proline-rich protein PRCC, Papillary renal cell carcinoma translocation-associated gene protein, PRCC, TPRC |
| Storage Conditions | -20℃ |
| Name | PRCC |
|---|---|
| Synonyms | TPRC |
| Function | May regulate cell cycle progression through interaction with MAD2L2. |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous in fetal and adult tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010]
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