PPP3R2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q96LZ3 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 19533 Da |
Antigen Region | 3-29 aa |
Gene ID | 5535 |
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Other Names | Calcineurin subunit B type 2, Calcineurin B-like protein, CBLP, Calcineurin BII, CNBII, PPP3R1-like, Protein phosphatase 2B regulatory subunit 2, Protein phosphatase 3 regulatory subunit B beta isoform, PPP3R2, CBLP, PPP3RL |
Target/Specificity | This PPP3R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-29 amino acids from the N-terminal region of human PPP3R2. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PPP3R2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPP3R2 |
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Synonyms | CBLP, PPP3RL |
Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. |
Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q63811}. Note=Localizes in the mitochondria in a SPATA33-dependent manner {ECO:0000250|UniProtKB:Q63811} |
Tissue Location | Testis-specific.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PPP3R2 is regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. This protein confers calcium sensitivity (By similarity).
References
He, Z.H., et al. Eur. J. Appl. Physiol. (2010) In press :
Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
Chow, R., et al. Biochem. Biophys. Res. Commun. 363(3):506-512(2007)
Saeki, M., et al. J. Biol. Chem. 282(16):11786-11794(2007)
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