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DUPD1 (DUSP27) (18A10) Mouse Monoclonal antibody
DUPD1 (DUSP27) (18A10) Mouse Monoclonal antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q68J44 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Calculated MW | 25336 Da |
| Gene ID | 338599 |
|---|---|
| Other Names | Dual specificity phosphatase 29 {ECO:0000312|HGNC:HGNC:23481}, Dual specificity phosphatase 27, Dual specificity phosphatase DUPD1, 3.1.3.16, 3.1.3.48, DUSP29 (HGNC:23481) |
| Storage Conditions | -20℃ |
| Name | DUSP29 (HGNC:23481) |
|---|---|
| Function | Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (PubMed:17498703). Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase (By similarity). Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity). |
| Cellular Location | Cytoplasm. Nucleus {ECO:0000250|UniProtKB:Q8BK84} |
Research Areas
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Application Protocols
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Cat# AP93840
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