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PRPC Rabbit Polyclonal Antibody

PRPC Rabbit Polyclonal Antibody

     
  •  - PRPC Rabbit Polyclonal Antibody AP93506
    Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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  • SPECIFICATION
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P02810
Reactivity Rat, Human
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 17015 Da
Additional Information
Gene ID 5554;5555
Other Names Salivary acidic proline-rich phosphoprotein 1/2, Db-s, PRP-1/PRP-2, Parotid acidic protein, Pa, Parotid double-band protein, Parotid isoelectric focusing variant protein, PIF-S, Parotid proline-rich protein 1/2, Pr1/Pr2, Protein C, Salivary acidic proline-rich phosphoprotein 1/2, Salivary acidic proline-rich phosphoprotein 3/4, Db-F, PIF-F, PRP-3/PRP-4, Protein A, Peptide P-C, PRH1
Storage Conditions-20℃
Protein Information
Name PRH1
Function PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.
Cellular Location Secreted.
Research Areas
Citations (0)
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Background

This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. Multiple distinct alleles of this locus including the parotid isoelectric-focusing variant slow (PIF-s), the parotid acidic protein (Pa), and the double band slow (Db-s) isoforms have been characterized. The reference genome encodes the Db-s allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Co-transcription of this gene with adjacent genes has been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015],

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$ 385.00
Cat# AP93506
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