POK6 Rabbit Polyclonal Antibody
POK6 Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | P63133 |
Reactivity | Rat, Human |
Host | Polyclonal, Rabbit,IgG |
Clonality | Polyclonal |
Calculated MW | 107703 Da |
Other Names | Endogenous retrovirus group K member 8 Pol protein, HERV-K115 Pol protein, HERV-K_8p23.1 provirus ancestral Pol protein, Reverse transcriptase, RT, 2.7.7.49, Ribonuclease H, RNase H, 3.1.26.4, Integrase, IN, ERVK-8 |
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Storage Conditions | -20℃ |
Name | ERVK-8 |
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Function | Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA. The RNase H domain of the reverse transcriptase performs two functions. It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid. Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome. Endogenous Pol proteins may have kept, lost or modified their original function during evolution. |

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