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KRA14 Rabbit Polyclonal Antibody
KRA14 Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P0C5Y4 |
| Reactivity | Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 12324 Da |
| Gene ID | 728255 |
|---|---|
| Other Names | Keratin-associated protein 1-4, High sulfur keratin-associated protein 1.4, Keratin-associated protein 1.4, KRTAP1-4, KAP1.4, KRTAP1.4 |
| Storage Conditions | -20℃ |
| Name | KRTAP1-4 |
|---|---|
| Synonyms | KAP1.4, KRTAP1.4 |
| Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Tissue Location | Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone |
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Provided below are standard protocols that you may find useful for product applications.
Background
The main structural proteins of mammalian hair fiber are the hair keratins (see MIM 601077) and the keratin-associated proteins (KAPs), which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins (Shimomura et al., 2002 [PubMed 12228244]).[supplied by OMIM, Jan 2009],
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