GRB2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC |
---|---|
Primary Accession | P62993 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | ASH; EGFRBP GRB2; Grb2; Growth factor receptor bound protein 2; Growth factor receptor bound protein 3; HT027; NCKAP2; SEM5; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 25206 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human GRB2 |
Description | Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GRB2 |
---|---|
Synonyms | ASH |
Function | Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. |
Cellular Location | Nucleus. Cytoplasm. Endosome Golgi apparatus {ECO:0000250|UniProtKB:Q60631} |
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