C Reactive Protein Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P02741 |
Clonality | Monoclonal |
Other Names | CRP; Pentraxin 1; PTX1; C reactive protein pentraxin related; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 25039 Da |
Dilution | WB 1:500~1:2000 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human C Reactive Protein |
Description | Serum CRP values are routinely measured to detect or monitor many human diseases and minor elevations of C-reactive protein are predictive of cardiovascular events in patients with coronary heart disease. CRP promotes host defense, is an efficient activator of the classical C cascade, and shown to be opsonic.The opsonic and C activation activities are responsible for the nonspecific host defense activities providing protection in the preimmune stage of acute infections. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CRP |
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Synonyms | PTX1 |
Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
Cellular Location | Secreted. |
Tissue Location | Found in plasma. |
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