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CCL23 / MIP3 Antibody

Rabbit mAb

     
  •  - CCL23 / MIP3 Antibody AP93174
    Western blot analysis of CCL23 / MIP3 expression in recombinant protein cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P55773
Clonality Monoclonal
Other Names C C motif chemokine ligand 23; C-C motif chemokine 23; C6 beta chemokine; CCL23; CCL23(30-99); Chemokine (C C motif) ligand 23; Chemokine CC motif ligand 23; ck beta 8; CKB8; Hmrp-2a; Macrophage inflammatory protein 3; MIP3; MPIF1; Myeloid progenitor inhibitory factor 1; SCYA23; Small inducible cytokine A 23; Small inducible cytokine subfamily A, member 23; Small-inducible cytokine A23;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 13411 Da
Additional Information
Dilution WB 1:500~1:2000 IHC 1:50~1:200
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human CCL23 / MIP3
Description Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name CCL23
Synonyms MIP3, MPIF1, SCYA23
Function Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23.
Cellular Location Secreted.
Tissue Location High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.
Research Areas
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