CD125 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q01344 |
Clonality | Monoclonal |
Other Names | CD125; CDw125; HSIL5R3; IL5R; IL5RA; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 47685 Da |
Dilution | WB 1:500~1:2000 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human CD125 |
Description | This is the receptor for interleukin-5. The alpha chain binds to IL5. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | IL5RA |
---|---|
Synonyms | IL5R |
Function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:9378992). Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1495999, PubMed:22528658). In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway (PubMed:9516124). |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Expressed on eosinophils and basophils. |

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