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CD125 Antibody

Rabbit mAb

     
  •  - CD125 Antibody AP93118
    Western blot analysis of CD125 in Human serum cell lysate.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q01344
Clonality Monoclonal
Other Names CD125; CDw125; HSIL5R3; IL5R; IL5RA;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 47685 Da
Additional Information
Dilution WB 1:500~1:2000
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human CD125
Description This is the receptor for interleukin-5. The alpha chain binds to IL5.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name IL5RA
Synonyms IL5R
Function Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:9378992). Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1495999, PubMed:22528658). In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway (PubMed:9516124).
Cellular Location Membrane; Single-pass type I membrane protein.
Tissue Location Expressed on eosinophils and basophils.
Research Areas
Citations (0)
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$ 350.00
$ 175.00
Cat# AP93118
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Availability: 4 weeks
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