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RASSF2 Antibody

Rabbit mAb

     
  •  - RASSF2 Antibody AP92898
    Western blot analysis of RASSF2 expression in Jurkat cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P50749
Clonality Monoclonal
Other Names CENP 34; RASFADIN; RASSF2;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 37790 Da
Additional Information
Dilution WB 1:500~1:2000
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human RASSF2
Description Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name RASSF2
Synonyms CENP-34 {ECO:0000303|PubMed:20813266}, K
Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Cellular Location Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 and STK4/MST1
Tissue Location Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Research Areas
Citations (0)
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$ 350.00
$ 175.00
Cat# AP92898
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