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EFTUD2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - EFTUD2 Antibody (Center) AP9288c
    Western blot analysis of EFTUD2 Antibody (Center) (Cat. #AP9288c) in A2058 cell line lysates (35ug/lane). EFTUD2 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - EFTUD2 Antibody (Center) AP9288c
    EFTUD2 Antibody (Center) (Cat. #AP9288c) IHC analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the EFTUD2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q15029
Other Accession O08810, Q5F3X4, A4FUD3
Reactivity Human
Predicted Bovine, Chicken, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 109436 Da
Antigen Region 257-284 aa
Additional Information
Gene ID 9343
Other Names 116 kDa U5 small nuclear ribonucleoprotein component, Elongation factor Tu GTP-binding domain-containing protein 2, SNU114 homolog, hSNU114, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, EFTUD2, KIAA0031, SNRP116
Target/Specificity This EFTUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-284 amino acids from the Central region of human EFTUD2.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEFTUD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EFTUD2
Synonyms KIAA0031, SNRP116
Function Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (PubMed:25092792, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:29301961, PubMed:29360106, PubMed:29361316, PubMed:30315277, PubMed:30705154). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (PubMed:16723661). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).
Cellular Location Nucleus
Research Areas
Citations (0)
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Background

EFTUD2 is component of the U5 snRNP complex required for pre-mRNA splicing.

References

Miele,A., et.al., J. Cell. Biochem. 102 (1), 136-148 (2007)
Koch,H.B., et.al., Cell Cycle 6 (2), 205-217 (2007)
Ewing,R.M., et.al., Mol. Syst. Biol. 3, 89 (2007)

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$ 182.50
$ 70.00
Cat# AP9288c
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