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P2Y12 Antibody

Rabbit mAb

     
  •  - P2Y12 Antibody AP92821
    Western blot analysis of P2Y12 expression in RAW 264.7 cell lysate.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession Q9H244
Reactivity Rat
Clonality Monoclonal
Other Names ADP glucose receptor; ADPGR; BDPLT8; HORK3; P2RY12; P2Y purinoceptor 12; P2Y12; P2Y12 platelet ADP receptor; Platelet ADP receptor; Purinergic receptor P2RY12; Purinergic receptor P2Y12; SP1999;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 39439 Da
Additional Information
Dilution WB 1:500~1:2000 IP 1:50
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human P2Y12
Description Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Involved in platelets aggregation.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name P2RY12
Synonyms HORK3
Function Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain
Research Areas
Citations (0)
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$ 350.00
$ 175.00
Cat# AP92821
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