Collagen III Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, IP |
---|---|
Primary Accession | P02461 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Alpha 1 type III collagen; COL3A1; Collagen III alpha 1 chain precursor; Collagen type III alpha ; EDS4A; Fetal collagen; Type III collagen; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 138564 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from Collagen III |
Description | Collagen type III occurs in most soft connective tissues along with type I collagen. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | COL3A1 |
---|---|
Function | Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793} |
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