Desmocollin 3 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, ICC |
---|---|
Primary Accession | Q14574 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | CDHF3; Desmocollin3; Desmocollin4; DSC; DSC1; DSC2; DSC3; DSC4; HTCP; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 99969 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from Desmocollin 3 |
Description | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | DSC3 |
---|---|
Synonyms | CDHF3, DSC4 |
Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome |
Tissue Location | Epidermis, buccal mucosa, esophagus and cervix. |
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