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C7 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | P10643 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 93518 Da |
| Antigen Region | 375-403 aa |
| Gene ID | 730 |
|---|---|
| Other Names | Complement component C7, C7 |
| Target/Specificity | This C7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-403 amino acids from the Central region of human C7. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | C7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | C7 |
|---|---|
| Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection.
References
Davila,S., et.al., Genes Immun. 11 (3), 232-238 (2010)
Kuijpers,T.W., et.al., Mol. Immunol. 47 (4), 671-677 (2010)
Wheeler,H.E., et.al., PLoS Genet. 5 (10), E1000685 (2009)
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