CNTP2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC |
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Primary Accession | Q9UHC6 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | AUTS15; CDFE; CNTNAP2; CNTP2; NRXN4; PTHSL1; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 148167 Da |
Dilution | WB 1:500~1:1000 IHC 1:100~1:500 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human CNTP2 |
Description | May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CNTNAP2 |
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Synonyms | CASPR2 {ECO:0000303|PubMed:10624965}, KI |
Function | Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. |
Cellular Location | Membrane {ECO:0000250|UniProtKB:Q9CPW0}; Single- pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9CPW0}. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:Q9CPW0}. Note=Expressed in the juxtaparadonal region. {ECO:0000250|UniProtKB:Q9CPW0} |
Tissue Location | Predominantly expressed in nervous system. |

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