PCBP1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
---|---|
Primary Accession | Q15365 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Alpha-CP1; hnRNP E1; HNRPE1; HNRPX; PCBP1; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 37498 Da |
Dilution | WB 1:500~1:2000 IP 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human PCBP1 |
Description | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | PCBP1 {ECO:0000303|PubMed:7607214, ECO:0000312|HGNC:HGNC:8647} |
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Function | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:15731341, PubMed:7556077, PubMed:7607214, PubMed:8152927). Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity). |
Cellular Location | Nucleus. Cytoplasm. Note=Loosely bound in the nucleus (PubMed:7607214). May shuttle between the nucleus and the cytoplasm (PubMed:7607214). |
Tissue Location | Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. |
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