APLP2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q06481 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Aplp2; APPH; APPL2; CDEBP; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 86956 Da |
Dilution | WB 1:1000~1:5000 IHC 1:50~1:200 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human APLP2 |
Description | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | APLP2 (HGNC:598) |
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Function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Nucleus |
Tissue Location | Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues |
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