GAA Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P10253 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Acid maltase; GAA; Glucosidase alpha acid; LYAG; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 105324 Da |
Dilution | WB 1:500~1:2000 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human GAA |
Description | Essential for the degradation of glygogen to glucose in lysosomes. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GAA |
---|---|
Function | Essential for the degradation of glycogen in lysosomes (PubMed:14695532, PubMed:18429042, PubMed:1856189, PubMed:7717400). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed:29061980). |
Cellular Location | Lysosome. Lysosome membrane |
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