ASS1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, IP |
---|---|
Primary Accession | P00966 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Argininosuccinate synthase 1; ASS; ass1; ASSA; Citrulline aspartate ligase; CTLN1; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 46530 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:500 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human ASS1 |
Description | Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3. Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | ASS1 (HGNC:758) |
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Function | One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. |
Cellular Location | Cytoplasm, cytosol |
Tissue Location | Expressed in adult liver. |
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