Galactosidase alpha Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, IP |
---|---|
Primary Accession | P06280 |
Clonality | Monoclonal |
Other Names | Alpha gal A; GALA; Galactosidase, alpha; GLA; Melibiase; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 48767 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:80 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Galactosidase alpha |
Description | Defects in GLA are the cause of Fabry disease (FD) [MIM:301500]. FD is a rare X-linked sphingolipidosis disease where glycolipid accumulates in many tissues. The disease consists of an inborn error of glycosphingolipid catabolism. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GLA (HGNC:4296) |
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Function | Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome. |
Cellular Location | Lysosome. |
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