Lactoferrin Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC, IP |
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Primary Accession | P02788 |
Clonality | Monoclonal |
Other Names | GIG12; HLF2; Kaliocin 1; Lactoferrin; Lactotransferrin; LTF; Neutrophil lactoferrin; Talalactoferrin; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 78182 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Lactoferrin |
Description | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | LTF (HGNC:6720) |
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Synonyms | GIG12, LF |
Function | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. |
Cellular Location | [Isoform 1]: Secreted. Cytoplasmic granule. Note=Secreted into most exocrine fluids by various endothelial cells Stored in the secondary granules of neutrophils |
Tissue Location | High levels are found in saliva and tears, intermediate levels in serum and plasma, and low levels in urine. In kidney, detected in the distal collecting tubules in the medulla but not in the cortical region or in blood vessels. Detected in peripheral blood neutrophils (at protein level). Isoform 1 and isoform DeltaLf are expressed in breast, prostate, spleen, pancreas, kidney, small intestine, lung, skeletal muscle, uterus, thymus and fetal liver Isoform 1 is expressed in brain, testis and peripheral blood leukocytes; isoform DeltaLf is barely detectable in these tissues Isoform DeltaLf is expressed in placenta, liver and ovary; isoform 1 is barely detectable in these tissues. In kidney, isoform 1 is expressed at high levels in the collecting tubules of the medulla but at very low levels in the cortex. |
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