RAP1GAP Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, IP |
---|---|
Primary Accession | P47736 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | RAP1GA1; Rap1GAP; Rap1GAP1; RAP1GAPII; RAPGAP; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 73361 Da |
Dilution | WB 1:1000~1:5000 IHC 1:100~1:500 ICC/IF 1:50~1:200 IP 1:50 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human RAP1GAP |
Description | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | RAP1GAP |
---|---|
Synonyms | KIAA0474, RAP1GA1 |
Function | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP- bound state. |
Cellular Location | Golgi apparatus membrane; Peripheral membrane protein |
Tissue Location | Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues |
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