Brachyury Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, IP |
---|---|
Primary Accession | O15178 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Brachyury homolog; Bry; Protein T; SAVA; TFT; T-box transcription factor T; TBXT; Brachyury protein; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 47443 Da |
Dilution | WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:100~1:500 IP 1:100 FC 1:100 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Brachyury |
Description | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | TBXT (HGNC:11515) |
---|---|
Synonyms | T |
Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
Cellular Location | Nucleus |
Tissue Location | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level) |
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