PBRM1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC |
---|---|
Primary Accession | Q86U86 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | BAF180; hPB1; PB1; Pbrm1; polybromo 1; Polybromo-1D; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 192948 Da |
Dilution | WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:100 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human PBRM1 |
Description | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Act as a negative regulator of cell proliferation. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | PBRM1 |
---|---|
Synonyms | BAF180, PB1 |
Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. |
Cellular Location | Nucleus |
Tissue Location | Widely expressed.. |
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