NKX2.2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC, ICC |
---|---|
Primary Accession | O95096 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Homeobox protein Nkx 2.2; NK 2 homolog B; NK2 homeobox 2; NKX2 2; NKX22; Nkx2b; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 30133 Da |
Dilution | IHC 1:100~1:500 ICC/IF 1:50~1:100 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human NKX2.2 |
Description | May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | NKX2-2 |
---|---|
Synonyms | NKX2.2, NKX2B |
Function | Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |

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